A new Commission from The Lancet and the University of Oslo, of which Dr. Jennifer Leaning, director of Harvard’s FXB Center Director, and Dr. Julio Frenk, dean of Harvard School of Public Health, are both members, has issued an urgent call for a reform of global decision-making to address health inequalities worldwide. The current global governance system fails to protect the public’s health and the distribution of health risks remains unjustly concentrated, the Commission on Global Governance for Health reports today in an extensive paper published by the Lancet.