A collaborative study including Dr. Raymona Lawrence, associate professor of community health behavior and education, and Dr. Gulzar Shah, associate dean of research at the Jiann-Ping Hsu College of Public Health Georgia Southern University examined athletes' perceptions of national collegiate athletic association-mandated sickle cell trait screening: insight for academic institutions and college health professionals. The study objective was to explore athletes' perspectives of National Collegiate Athletic Association (NCAA)-mandated sickle cell trait (SCT)-screening policy by examining race- and gender-related differences in athletes' perceptions regarding risk of having SCT and concern about loss of playing time.