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PHR Article of the Week: Administration Time Between Seasonal Live Attenuated Influenza Vaccine and Trivalent Influenza Vaccine During the “Stop Flu at Schools” Campaign Hawaii, 2009

In the Public Health Reports, May/June 2014 issue, Dr. Meera Sreenivasan, former CDC EIS officer and current Kaiser Permanente Hawaii Medical Group practitioner, and Dr. Hua He and Dr. Sarah Park from the Hawaii Department of Health, report the administration time between seasonal live-attenuated influenza vaccine and trivalent influenza vaccine during the “Stop Flu at School” Campaign, Hawaii, 2009.

The study focused on whether the administration time differed between seasonal intranasal live-attenuated influenza vaccine (LAIV) and seasonal injectable trivalent inactivated influenza vaccine (TIV) during Hawaii’s 2009 school-located influenza vaccination clinics. This information is useful for public health response and allows further investigation into possible differences between the two vaccines.

A total of 4,701 students were enrolled in the study, and administration time was obtained for 3,869 (82 percent) students (1,492[39 percent] LAIV and 2,377[61 percent] TIV). The mean administration time for LAIV was 62 seconds and for TIV was 90 seconds, a difference of 28 seconds (p<0.01). Although results indicated that both LAIV and TIV can be administered rapidly among school-aged populations, LAIV was faster to administer. This finding, in addition to the greater immunogenicity of LAIV compared with TIV among children, may be an important consideration for public health administrator in planning school-located mass vaccination clinics and encouraging patient acceptance of this vaccine.

This week’s PHR feature article, Administration Time Between Seasonal Live-Attenuated Influenza Vaccine and Trivalent Influenza Vaccine During the “Stop Flu at School” Campaign Hawaii, 2009  will be open access through July 3, 2014. For full access to current content, visit the Public Health Reports website to subscribe.